A.B. Simpson emphasizes the significance of practical prayer in everyday life, illustrating how prayer can guide us in our daily affairs, provide wisdom, and bring healing. He highlights that prayer is not just for personal needs but also for the benefit of others, encouraging believers to pray fervently and expectantly. Simpson shares biblical examples, such as David and Ezra, to demonstrate how prayer can lead to divine intervention in trials and challenges. He also stresses the importance of prayer in times of joy and sickness, reminding us that prayer is a powerful tool for both personal and communal healing. Ultimately, he calls for a deeper commitment to prayer as a means of connecting with God and serving others.