Mike Bickle emphasizes the significance of Isaiah 2 as a foundational text for understanding the end times, highlighting that Isaiah was entrusted with more revelation about the end times than any other prophet. He explains that the forerunner message reveals God's plan to establish Jerusalem as the epicenter of His reign, filled with love and glory, and that the nations will be drawn to it. Bickle encourages critical thinking and interaction among believers to grasp the fullness of God's message, asserting that the end times are not a doom and gloom narrative but a glorious love story. He stresses the importance of understanding the connection between the earthly and heavenly Jerusalems and the role of believers in this divine plan.