Mike Bickle emphasizes the gladness of Jesus and the significance of praying in tongues as a means of personal edification and divine communication. He encourages believers to engage deeply with the Holy Spirit, highlighting that speaking in tongues allows individuals to receive mysteries and insights about their own hearts and the Word of God. Bickle shares his personal journey from skepticism to embracing the gift of tongues, urging the congregation to dedicate time to pray in the Spirit for spiritual growth and revelation. He stresses the importance of consistency in prayer and the transformative power it can have over time.