Charles Finney delivers a powerful sermon on 'Death to Sin,' emphasizing that true freedom from sin comes through a spiritual death that annihilates selfishness and fosters perfect love for God and others. He outlines various types of death mentioned in the Bible, clarifying that the death referred to in Romans 6:7 is a death to sin, which is achieved through the baptism of the Holy Spirit. Finney stresses that this transformation is not accomplished by mere resolutions but requires a complete surrender to God's will and the purifying influence of the Holy Spirit. He encourages believers to seek this state of being dead to sin actively, as it leads to a life wholly devoted to God's glory. The sermon concludes with a call to recognize the necessity of total abstinence from sin to maintain spiritual life.