A.B. Simpson explores the story of Esther, emphasizing how God orchestrates events for His glory and the deliverance of His people. He highlights Esther's courage to act in a time of crisis, reminding us that our positions and gifts are divine trusts meant for service. The sermon illustrates how God uses even the wrath of man to fulfill His purposes, and how He prepares His people for significant moments in history. Simpson encourages believers to recognize their roles in God's plan and to act decisively when called upon, as Esther did, for such a time as this.