David Wilkerson emphasizes the essential ministry calling of every Christian, which is to behold the face of Christ through devoted worship. He explains that this ministry does not require special gifts but is fundamental for all believers, as it must precede any other ministry efforts. Wilkerson highlights the importance of fixing our gaze on Jesus, indicating that true transformation occurs when we earnestly seek God's presence. He references Paul's teaching in 2 Corinthians, illustrating that as we focus on Christ, we are progressively transformed into His image by the Holy Spirit. This intimate communion with God is vital for spiritual growth and effectiveness in ministry.