John Gill emphasizes the importance of temperance and patience in the Christian life, arguing that knowledge alone is insufficient if it is not accompanied by a life of self-control and purity. He warns against the dangers of intemperance, particularly in relation to the teachings of false prophets like Simon Magus, who equated knowledge with salvation despite leading immoral lives. Gill highlights that true knowledge must be coupled with love and that patience is essential for enduring the challenges of faith, including afflictions and persecutions. He also discusses the significance of godliness, which encompasses both internal grace and external worship, as vital components of a believer's life.

Ver. 6. And to knowledge, temperance,.... Avoiding all excess in eating and drinking, and all impure and unclean lusts; for it signifies nothing what a man knows, or professes to know, if his life is a scene of intemperance and debauchery: this seems to be levelled against the followers or Simon Magus, who ascertained salvation to knowledge, though the life was ever so impure, Moreover, this may include abstinence, not only from hurtful lusts, but from the use of things indifferent, when the peace and comfort of a weak brother are endangered; for then to knowledge must be added love, otherwise that knowledge will not be right, at least not rightly used; see 1Co 8:1, and to temperance, patience; which is necessary to the running of the Christian race, which is attended with many difficulties and exercises; and under affliction from the hand of God, that there be no murmuring nor repining; and under reproaches and persecutions from men, that they faint not, and are not discouraged by them; and in the expectation of the heavenly glory: this is proper to be superadded to the former, because there may be intemperance in passion, as well as in the use of the creatures; a man may be inebriated with wrath and anger, and overcome with impatience, as well as with wine and strong drink: and to patience, godliness; either internal, which is distinguished from bodily exercise, or outward worship, and lies in the inward and powerful exercise of grace, as faith, hope, love, fear, &c. and the Syriac version here renders it, "the fear of God": or rather external, and intends the whole worship of God, as prayer, praise, hearing of the word, and attendance on all ordinances.