Samuel Logan Brengle emphasizes that holiness is often misunderstood; it is not a constant state of joy, freedom from temptation, infirmities, or afflictions. Instead, holiness is characterized by a pure heart and a deep relationship with God, allowing for growth and development even amidst trials. He illustrates that even holy figures like Jesus and Paul faced temptations and suffering, yet their holiness was defined by their love, patience, and perseverance through difficulties. Brengle concludes that true holiness is a state of conformity to God's nature, achieved through faith and the work of the Holy Spirit, leading to a life of peace and joy despite life's challenges.