Chuck Smith discusses 'The Curse on Canaan' as he explores the sinful nature of humanity, which persists even after the flood. He emphasizes that Noah's curse on Canaan was misinterpreted historically to justify slavery, which is a perversion of scripture. Smith clarifies that the descendants of Canaan were not destined for servitude but contributed significantly to civilization, particularly through the Phoenicians. He also highlights the genealogical significance of Noah's sons, particularly Shem, from whom Abraham and ultimately Jesus would descend. The sermon concludes with a reflection on the importance of understanding biblical history and its implications for faith today.