C.H. Spurgeon emphasizes the importance of full reliance on God, particularly for those in need. He encourages the needy to cry out to God directly rather than seeking help from friends, as true assistance comes from the Lord. Spurgeon reassures that God hears the cries of the helpless and will provide for both temporal and spiritual needs. He urges listeners to approach God as beggars, relying solely on His grace and mercy. Ultimately, Spurgeon reminds us that God has never failed and will not fail those who trust in Him.