Andrew Murray emphasizes the call for Christians to live an unworldly life, highlighting the pervasive influence of a society estranged from God that can subtly weaken our spiritual vitality. He asserts that the Spirit of God empowers believers to overcome this worldly spirit, enabling them to embrace a heavenly life that transcends worldly values and threats. Murray encourages Christians to cultivate a deep fellowship with God, allowing His light and strength to guide them in their earthly lives, thus perpetuating the unworldly nature of Christ among His followers.