John Nelson Darby emphasizes the duality of ministries in 2 Corinthians 4 and 5, contrasting the ministry of the Spirit with that of the Old Testament prophets. He explains that true ministry requires personal possession of the truths we share, highlighting the transformative power of the Holy Spirit in revealing the glory of God through Jesus Christ. Darby illustrates how believers, filled with the Holy Spirit, are called to reflect Christ's glory and await His return, while navigating the trials of life as vessels of His grace. He encourages Christians to recognize their identity in Christ and the hope of eternal glory, urging them to live in light of this truth.