Chuck Smith emphasizes the importance of listening in prayer, asserting that prayer should not be a one-sided conversation but a dialogue with God. He illustrates that the mightiest men of prayer, such as Moses, Samuel, and Elijah, were those who took the time to listen and know God deeply. Smith encourages believers to study the Bible not just for knowledge but to truly understand and connect with God, suggesting practical ways to engage with Scripture thoughtfully and prayerfully. He highlights that faith comes from hearing God's word, which requires a receptive heart and mind.