Chuck Smith explores the theme of prevailing with God through the story of Jacob, who confronts his past and wrestles with God. Jacob's journey illustrates the struggle between self-reliance and surrendering to God's will, as he seeks solace and blessing after years of turmoil. The sermon emphasizes that true power comes from submission to God, as Jacob learns to let go of his past and trust in God's grace. Ultimately, Smith encourages listeners to allow God to intervene in their lives, providing healing and reconciliation with their past.