Smith Wigglesworth emphasizes the importance of the word of knowledge through the Holy Spirit, urging believers to fully embrace God's revelation and mix it with faith for it to be effective. He highlights that Christ is the unshakeable foundation upon which we must build our lives, and that the gifts of the Spirit, including knowledge, are essential for spiritual growth and revival. Wigglesworth encourages believers to seek a deeper relationship with God, stressing that true knowledge and faith come from the Spirit, leading to transformation and empowerment to impact the world. He also shares personal experiences to illustrate the power of faith and the necessity of being fully yielded to the Holy Spirit for effective ministry.