Theodore Epp discusses the connection between sickness and sin as outlined in James 5:13-16, emphasizing the role of spiritual leaders in addressing ailments that stem from sin. He explains that the elders are to be called for prayer and anointing with oil, which was a common medical practice of the time, highlighting the importance of combining prayer with known medical treatments. Epp clarifies that while divine healing is possible, the passage encourages the use of medicine alongside faith in God's healing power. He stresses the need for self-examination to avoid judgment, as noted in 1 Corinthians 11:31.