Smith Wigglesworth emphasizes the transformative power of the Word of God, which penetrates the depths of our being and purifies our souls. He highlights that through Christ's resurrection, we can experience a divine change that dethrones negativity and builds a foundation of holiness and humility. By surrendering to God, we can let go of our weaknesses and embrace the life and power of Christ within us. The sermon calls for a deep desire for God's presence, leading to a life that reflects the character of Jesus. Ultimately, it encourages believers to trust in God's ability to uphold them as they seek transformation.