A.W. Tozer emphasizes that true ministers are called by God rather than choosing the ministry for themselves, often experiencing reluctance in their calling. He reflects on biblical figures like Moses, who resisted their divine commission but ultimately surrendered to the compelling call of the Spirit. Tozer warns against those who rush into ministry without understanding its sacred nature, highlighting that genuine ministers feel an inward pressure to preach the gospel, echoing Paul's sentiment of woe if they do not. The sermon serves as a reminder of the seriousness and weight of the ministerial calling, urging faithfulness to God's call.