John Nelson Darby addresses the concept of a clergyman as a significant sin against the Holy Ghost, arguing that this notion substitutes human authority for the divine power of the Holy Spirit, leading to the church's destruction. He emphasizes that true ministry should be based on the Spirit's guidance rather than human appointment, and warns against the dangers of clericalism, which he believes hinders the work of God. Darby reflects on his own journey of faith, recognizing the importance of being united with Christ and the role of the Holy Spirit in the life of believers. He calls for a return to scriptural principles and a rejection of worldly influences that corrupt the church's mission. Ultimately, he urges Christians to seek the Holy Spirit's guidance and to discern the true nature of the church as God's dwelling place.