D.L. Moody emphasizes the importance of casting our burdens upon the Lord, as doing so frees us from the torment of anxiety and fear. He explains that taking on our own cares leads to an uneasy burden, while trusting in God allows us to find peace and relief. Moody encourages believers to rely on God's ability to handle our concerns, reminding us that He invites us to lay our worries at His feet.

C.H. Spurgeon emphasizes the importance of casting our cares upon God, reminding Christians that they should not carry burdens that God is willing to bear. He encourages believers to trust in God's providence, assuring them that their troubles are light compared to His strength. Spurgeon reassures the suffering that God is attentive to their needs and will provide comfort and healing. He urges the faithful to abandon despair and embrace hope, as God’s grace remains constant even in tribulation. Ultimately, he calls for a serene life by entrusting all concerns to the God who cares deeply for His children.

A.W. Tozer emphasizes the overwhelming burdens that people face daily, leading to mental distress and a reliance on inadequate solutions from society. He argues that while physical comforts have increased, the emotional and spiritual burdens have multiplied, leaving many in despair. Tozer encourages believers to cast their burdens upon the Lord, who is capable of carrying them, thus allowing for a more joyful and purposeful life. He highlights the inadequacy of human solutions to address the deep-seated issues of the heart. Ultimately, Tozer calls for a deeper trust in God as our ultimate caregiver.