Mike Bickle emphasizes the growing call for full-time intercessory missionaries within the body of Christ, highlighting the biblical foundation and historical precedent for this vocation. He notes the significant increase in 24-hour prayer ministries globally, from 25 to over 20,000 in just 30 years, indicating a divine movement led by the Holy Spirit. Bickle encourages believers to support this calling, even if they are not personally called to it, and stresses the importance of prayer as a central activity in the church. He references biblical examples, particularly from the Old Testament, to illustrate the role of intercessors and their vital function in God's plan. Ultimately, he calls for a recognition of individual callings while affirming the necessity of intercessory prayer in the end times.