Charles Finney addresses ministers of the Gospel, urging them to overcome the fear of changing their opinions on religious matters. He highlights the unreasonable public sentiment that discourages the advancement of religious knowledge, suggesting that it is seen as a crime to discover new truths that past generations did not know. Finney emphasizes the importance of continual learning and growth in understanding God's word, arguing that the church must not remain stagnant but should embrace innovation in theology. He calls for ministers to reject the prejudice against new ideas and to boldly proclaim the truths they discover, as this is essential for the church's spiritual maturity.