David Wilkerson emphasizes that when engaged in a divine mission, one must remain steadfast against the attacks of Satan, who seeks to hinder God's work through distractions and discouragement. He illustrates this through Nehemiah's unwavering commitment to rebuilding the walls of Jerusalem despite facing opposition from prominent leaders who attempted to undermine his efforts. Nehemiah's refusal to be distracted by their plots serves as a powerful reminder that God's calling must take precedence over the noise of criticism and fear. Ultimately, the completion of the wall stands as a testament to God's faithfulness and support in the face of adversity.