F.B. Meyer explores the story of Hagar, the slave girl, emphasizing the complexities of faith and the self-life in the journey of obedience to God. He highlights how Abraham and Sarah's impatience led to a decision that caused great sorrow and conflict, illustrating the dangers of taking matters into our own hands rather than waiting for God's timing. Meyer points out that even in our struggles, God sees us and calls us to return and submit to His will, promising that obedience will lead to blessings. The sermon serves as a reminder of the importance of trusting God's plan and the consequences of human expediency.