A.W. Tozer emphasizes that while human intellect cannot fully comprehend God, it is through the Spirit that we can experience and know Him. He explains that true knowledge of God transcends intellectual understanding and is revealed to the spirit of man. Tozer highlights the mystery of God's nature and the limitations of human wisdom in knowing Him. He asserts that God can reveal Himself to those whom He chooses, and this revelation is not merely intellectual but intuitive, allowing for a deeper connection with the divine.