C.H. Spurgeon emphasizes God's sovereign power to protect His people, illustrating that just as He can silence the tongues of dogs, He can also grant peace amidst adversaries. He reassures believers that despite the noise and threats from the ungodly, God can keep them safe and unhurt, much like Daniel in the lion's den. Spurgeon encourages the faithful to seek God's intervention in their troubles, trusting that His grace creates a clear distinction between the righteous and the wicked. The sermon calls for a deep reliance on God's power to provide peace and safety in the face of opposition.