John Wesley emphasizes the biblical command for children to obey their parents, highlighting that this principle is universally recognized and rooted in both natural law and divine revelation. He explains that obedience is not only a duty but also brings blessings, as it is pleasing to God and is the first commandment with a promise. Wesley urges parents to instill this obedience from a young age, warning against the dangers of indulgence and the consequences of allowing children to act on their own will. He calls for a serious commitment from both parents and children to uphold this commandment, framing it as essential for spiritual well-being and familial harmony.