Mike Bickle discusses 'The Seven Longings of the Human Heart,' emphasizing that these longings are divinely designed cravings within us that reflect God's personality. He explains that while these longings can lead us to seek fulfillment in unhealthy ways, they ultimately point us back to God, who can satisfy them. Bickle highlights the importance of understanding these longings to deepen our intimacy with God and live fully alive in our spirits. He encourages believers to pursue these longings through prayer, worship, and a revelation of God's beauty, assuring that they will be fully satisfied in the resurrection.