David Wilkerson addresses the dangerous nature of harboring resentment against God, highlighting how many believers secretly hold grudges due to unmet expectations or unanswered prayers. He uses the story of Jonah, who became angry when God spared Ninevah after their repentance, to illustrate how disappointment can lead to a sense of betrayal and entitlement to anger. Wilkerson emphasizes that while God understands our pain, allowing bitterness to fester can lead to destruction. He encourages believers to seek healing from resentment and trust in God's plans for restoration, reminding them that God rewards those who diligently seek Him.