Robert Murray M'Cheyne emphasizes the importance of coming to Jesus, urging both children and adults to approach Him without hesitation. He reflects on the unconditional love of Jesus, who welcomes all, regardless of their past or the world's judgment. M'Cheyne encourages believers to prioritize their relationship with Christ over worldly distractions and to find solace in His acceptance and grace. The sermon highlights the transformative power of faith and the joy of running to Jesus as the ultimate source of hope and salvation.