Zac Poonen emphasizes the importance of being 'in the Spirit' daily, particularly as we enter a new year. He explains that the early disciples gathered on the Lord's Day to strengthen one another, free from the constraints of special days, and that being in the Spirit allows us to hear God's voice amidst the distractions of the world. Poonen likens our minds to a radio, suggesting that tuning into spiritual matters enables us to receive divine messages, while tuning into worldly concerns leads to confusion and anxiety. He challenges believers to remain sensitive to sin and humble before God to fully experience His guidance and communication. As we embark on a new year, he encourages everyone to cultivate a spirit-filled life to hear the Lord's voice clearly.