Thomas Brooks emphasizes the dangers of ignorance in his sermon 'Ignorant People,' arguing that while some may believe ignorance fosters devotion, the Bible clearly states it leads to destruction. He cites Hosea 4:6 to illustrate that lack of knowledge results in ruin, and Matthew 22:29 to highlight that error stems from not knowing the Scriptures. Brooks warns that ignorance enslaves individuals to sin and makes them vulnerable to Satan's traps, ultimately leading to a life devoid of understanding and filled with misery. He concludes that ignorance not only breeds sin but also makes individuals indifferent to their actions against God and their own souls.

The Catholic Church says that ignorance is the mother of devotion. But the Scripture says that it is the mother of destruction. 'My people are destroyed for lack of knowledge.' Hosea 4:6 'You are in error because you do not know the Scriptures.' Matthew 22:29 Ignorance is the mother of mistake, and the cause of trouble, error, and of terror. Ignorance is the highway to hell, and it makes a man both a prisoner and a slave to the devil at once. Ignorance unmans a man; it makes a man a beast, yes, makes him more miserable than the beast which perishes. There are none so easily nor so frequently captured in Satan's snares—as ignorant people. They are easily drawn to dance with the devil all day—and to dream of supping with Christ at night. Sin at first was the cause of ignorance—but now ignorance is the cause of all sin. There are none so frequent, and so impudent in the ways of sin—as ignorant people. They care not, nor mind not what they do, nor what they say against God, Christ, heaven, holiness, and their own souls.