Edward Payson preaches about the need for someone to undertake for us in various aspects of life, including supporting and comforting us through trials, guiding us, assisting in overcoming spiritual enemies, and pleading our cause in heaven. He emphasizes that the only one able and willing to undertake for us is the Lord Jesus Christ, who promises to help all who come to Him in faith. Payson urges the congregation to apply to Christ for help, emphasizing the importance of a living faith that manifests in obedience and active service to God.

Thomas Bradbury preaches on the spiritual instruction found in John 12:27, where Jesus expresses His soul's trouble and submission to the Father's will. Bradbury emphasizes the deep suffering of Christ physically, mentally, and spiritually, as He faced the weight of humanity's sins and sorrows. He highlights the importance of experiencing a spiritual oneness with Christ in His sufferings to truly understand the depth of His love and compassion. Bradbury encourages believers to find comfort in Christ's sufferings and to trust in God's sovereignty even in the midst of trials and tribulations.

J.C. Philpot preaches on the deep reliance of God's people on Him alone for help and deliverance, emphasizing the need for a spiritual understanding of the malady of sin, the knowledge of the remedy found in God, and the application of that remedy to the soul. He delves into the various maladies of sin such as blindness, deafness, hard-heartedness, unbelief, and other corruptions, highlighting the necessity for God's healing touch in each area. Philpot stresses the importance of feeling the guilt, filth, and power of sin, and the ultimate salvation that comes from God alone, leading to a heartfelt acknowledgment that God is worthy of all praise.