In this sermon, the speaker shares a personal story of a minister who spent 40 years preaching rules and regulations before truly preaching about Jesus. The speaker emphasizes the importance of recognizing and seizing open doors of opportunity that God presents to us. He mentions the apostle Paul's experience in Ephesus, where a great door for effective work opened for him, despite facing opposition. The speaker encourages the congregation to embrace the open doors God provides and to hold on to their spiritual blessings.

Charles Finney addresses Henrietta Bissell, sharing the progress of his ministry in England, where he has been met with both enthusiasm and opposition. He recounts the overwhelming response to his preaching, with churches filled to capacity and many conversions taking place. Despite facing criticism and warnings from other ministers, Finney emphasizes the importance of standing firm in truth and the power of God to transform lives. He expresses gratitude for the support he receives and the collaborative spirit among different denominations in the revival efforts. Finney encourages prayer for the ongoing work and the need for faith in God's ability to bring about change.

Isaac Errett preaches about the great and effectual doors that God opens for preaching the gospel, emphasizing the importance of seizing opportunities to share the Word. He highlights the providential openings granted by God for success in spreading the gospel, stressing the need for divine providence and human agency to work together. Errett discusses the significant opposition faced in the form of Roman Catholicism, rationalism, and the secular spirit of the age, which hinders missionary efforts. He calls for a revival of prayer, humility, and devotion to God's will to overcome selfishness and indifference in advancing the kingdom of God.

J.C. Philpot preaches about the symbolic representation of the Church of God in its triumphant and militant states as depicted in the visions of John and Isaiah. He delves into the mystical nature of the heavenly city seen by John, contrasting it with the strong city described by Isaiah, symbolizing the Church in its glorious and suffering conditions. Philpot emphasizes the role of ministers as servants, stewards, labourers, and leaders in guiding believers through the gates of regeneration and faith, highlighting the spiritual journey and struggles faced in entering the heavenly city.

Zac Poonen preaches on the significance of being an overcomer, emphasizing that if we are in God's will as overcomers, no door will remain closed to us. God strategically shuts certain doors to prevent us from straying into unprofitable paths, ensuring we walk in His ordained ways. Just like in Jonah's life, God orchestrates the opening and closing of doors to guide us back to His perfect will, even if it means starting afresh. As wholehearted disciples seeking to glorify God, we can trust that God holds the key to every door, opening and closing them at the right time to align us with His divine purpose.

A.B. Simpson emphasizes the urgency of the missionary call, likening it to life-and-death emergencies that demand immediate action. He highlights the dire spiritual needs of humanity, the vast number of souls yet unreached, and the swift passage of time as reasons for Christians to actively engage in evangelism. Simpson calls for a courageous response to the open doors for spreading the Gospel, urging believers to 'redeem the time' and fulfill their obligation to share Christ with the world. He warns that the opportunity for evangelization may close if not acted upon swiftly, and he encourages steadfastness in the face of opposition. Ultimately, he inspires a sense of responsibility and urgency in the mission of the Church.

J. Stuart Holden emphasizes the challenging yet rewarding nature of Christian witness, highlighting the personal growth that occurs when faith is tested against difficult circumstances. He encourages facing obstacles with the power of Christ, as they are essential for personal development. Holden urges believers to focus on the open door of opportunity rather than being consumed by adversaries, reminding them that Christ undertakes every task with them, making them more than conquerors through His love.