Keith Simons teaches on Psalm 22, emphasizing its dual significance as a reflection of David's suffering and a prophetic foreshadowing of Christ's crucifixion. He explores the imagery of the psalm, likening David's plight to that of a deer pursued by predators, and highlights the deep anguish expressed in the verses, particularly the cry of abandonment. Simons illustrates how David's trust in God amidst despair serves as a model for believers, affirming that God hears the cries of the afflicted and ultimately delivers them. The sermon culminates in the declaration of God's faithfulness and the universal call to worship Him for His righteousness and salvation.