J.R. Miller discusses Paul's third missionary journey in Ephesus, emphasizing the city's significance as a center of influence and the initial rejection Paul faced from the Jews. Despite this, Paul preached boldly in a public hall for two years, leading to widespread dissemination of the gospel and the establishment of churches. The sermon highlights the extraordinary miracles performed through Paul, showcasing the divine power of Christianity compared to the failed attempts of magicians. The transformation of new believers, who openly confessed their sins and burned their magic books, illustrates the profound impact of Christ's power in their lives. Miller concludes by urging believers to renounce sin and choose righteousness, as true faith is evidenced by the fruits it produces.