R.A. Torrey emphasizes Jesus as the Good Shepherd in John 10:1-21, contrasting Him with false shepherds who seek to harm the sheep. He explains that true shepherds enter through Christ, while thieves and robbers come to steal and destroy. The Good Shepherd knows His sheep intimately, lays down His life for them, and offers them abundant life. Torrey highlights the importance of recognizing the voice of the true Shepherd and following Him, as true sheep will not follow strangers. The sermon calls believers to be vigilant against false teachings and to embody the love and sacrifice of Christ in their own lives.