D.L. Moody emphasizes the profound impact of encountering God, illustrating that true humility arises when one recognizes their own unworthiness in the presence of the divine. He references Isaiah, Daniel, and Job, who, despite their righteousness, were humbled and silenced upon seeing the Lord, realizing their own flaws and the need for repentance. Moody asserts that until individuals acknowledge their spiritual uncleanness, they will continue to boast of their own righteousness. The sermon highlights that true understanding of God's holiness leads to a necessary humility and silence before Him, as one cannot enter His kingdom without recognizing their own sinfulness.