John Gill expounds on 2 Peter 2:12, illustrating how certain individuals have descended to a level below that of animals, acting without reason and understanding. He emphasizes their moral corruption and the blindness that leads them to call good evil and evil good, likening them to brute beasts driven by instinct. These individuals are destined for destruction, as they are ensnared by their own wickedness and ignorance, speaking ill of things they do not comprehend, including angels, civil authorities, and the Scriptures. Ultimately, their servitude to corruption leads to their eternal perdition, a fate they are righteously appointed to by God.