K.P. Yohannan emphasizes the importance of letting go of past failures and regrets, using the metaphor of a man choosing between memory and eyesight to illustrate the need to focus on the present rather than being burdened by the past. He encourages listeners to learn from their experiences but not to be held captive by them, as each new day is a gift filled with hope and potential. The sermon highlights God's promise of a hopeful future, urging individuals to embrace today and the opportunities it brings.