David Wilkerson emphasizes that the last-days remnant, represented by the prophet Samuel, emerges from the ruins of a decaying church, birthed through deep grief and fervent prayer, much like Hannah's anguish for a child. He highlights that those who seek God's heart will face provocation from adversaries and often be misunderstood, as exemplified by Eli's misinterpretation of Hannah's heartfelt prayers. The sermon calls for believers to embody Hannah's spirit of intercession, dedicating themselves to prayer and being burdened for the state of God's house, ultimately leading to a ministry that touches others in their trials.