C.H. Spurgeon emphasizes the challenge of handling prosperity, noting that many Christians struggle more in abundance than in adversity. He points out that while it is easy to be humble in hardship, the true test lies in knowing how to abound without losing sight of God. Spurgeon highlights the importance of being spiritually grounded during times of plenty, as abundance can lead to forgetfulness and pride. He references the Apostle Paul, who learned to navigate both fullness and hunger with grace. The sermon concludes with a reminder to seek God's guidance in managing the blessings we receive.