Brian Guerin emphasizes the significance of knowing God's glory, particularly in the context of the relationship between fathers and sons, both spiritually and physically. He shares personal experiences and prophetic dreams that illustrate the importance of capturing and solidifying the spiritual harvest in this generation. Guerin encourages the congregation to remain open to the manifestations of God's glory, which may come in various forms, including signs and wonders, and stresses the need for cooperation between generations to fully embrace and experience God's presence. He highlights that the knowledge of God's glory will cover the earth, urging the church to welcome and honor the diverse ways God chooses to reveal Himself.