A.B. Simpson emphasizes that Christ has triumphed over our greatest adversaries: Sin, Sickness, Sorrow, and Satan. He assures us that we can transfer our burdens, including our sinfulness, to Jesus, who has already borne them for us. Simpson encourages believers to detach from their past infirmities and embrace the strength of Christ's life, rejoicing in tribulations and claiming victory over Satan, who has been defeated at the cross. He calls on the congregation to actively overcome these challenges by trusting in Christ's power and following Him. The message is a powerful reminder of the complete victory we have in Jesus.

Christ has overcome for us every one of our four terrible foes: Sin, Sickness, Sorrow, Satan. He has borne our sin, and we may lay all, even including our sinfulness itself, on Him. He has borne our sickness, and we may detach ourselves from our old infirmities and rise into His glorious life and strength. He has borne our sorrows, and we should not even carry a care, but rejoice evermore and even glory in tribulations. And He has conquered Satan for us, too, and left him nailed to the cross, spoiled and dishonored, a shadow of himself. And now we need only claim His full atonement and assert our victory, and so [overcome] him by the blood of the Lamb and by the word of our testimony (Revelation 12:11). Beloved, are we overcoming sin? Are we overcoming sickness? Are we overcoming sorrow? Are we overcoming Satan? Fear not, though the strife be long; Faint not, though the foe be strong; Trust thy glorious Captain's power; Watch with Him one little hour, Hear Him calling, "Follow Me, I have overcome for thee."