A.B. Simpson emphasizes that God often uses those who are despised and unpopular, reminding us that true recognition comes from God rather than man. He encourages believers to embrace their calling, even in the face of misunderstanding and prejudice, as many of God's greatest blessings lie beyond societal acceptance. Simpson asserts that the Holy Spirit is not ashamed to work through those who are marginalized, and that seeking God's will and glory should be our primary focus. He calls for courage to follow Christ, even when it means bearing reproach, assuring us that God will ultimately honor those who serve Him faithfully.

The Lord is still using the things that are despised. The very names of Nazarene and Christian were once epithets of contempt. No man can have God's highest thought and be popular with his immediate generation. The most abused men are often the most used. There are far greater calamities than to be unpopular and misunderstood. There are far worse things than to be found in the minority. Many of God's greatest blessings are lying behind the devil's scarecrows of prejudice and misrepresentation. The Holy Spirit is not ashamed to use unpopular people. And if He uses them, what need they care for men? Oh, let us but have God's recognition and man's notice will count for little, and God will give us all we need of human help and praise. Let us only seek God's will, His glory, His approval. Let us go for Him on the hardest errands and do for Him the most menial tasks. It will be honor enough that He sends us and uses us. Let us not fear in this day to follow Him outside the camp, bearing His reproach. By-and-by he will own our worthless name before the myriads of earth and heaven.