Thomas Brooks emphasizes the deep attachment sinners have to their lusts, illustrating that they often prioritize these over their most cherished relationships and even their relationship with God. He explains that the Holy Spirit's work is to help individuals recognize sin as their greatest enemy, leading them to despise and combat it. Brooks highlights that true grace instills a desire to rid oneself of all sin, equating the longing for freedom from sin to a slave's desire to escape chains. He asserts that a gracious heart would prefer to endure suffering rather than indulge in sin, as sin is the most defiling aspect of life. Ultimately, the sermon calls for a sincere commitment to forsake all forms of sin for the sake of spiritual purity.

Thomas Watson preaches about the characteristics of a godly man who does not indulge in any sin. He emphasizes that though sin may be present, a godly man does not continue in sin but seeks to rid himself of it. Watson highlights four types of sins that a godly man will not allow himself: secret sins, gainful sins, beloved besetting sins, and sins considered lesser by the world. He warns of the dangers and consequences of indulging in even one sin, stressing the importance of repentance and mortification of sin to maintain a pure and godly life.