John Wesley preaches on the folly of worldly wealth, using the parable of the rich fool from Luke 12:20 to illustrate the dangers of placing trust in material possessions rather than in God. He emphasizes that true wisdom lies in recognizing the transient nature of life and the importance of using our resources to help others rather than hoarding them for ourselves. Wesley warns that the pursuit of earthly treasures leads to spiritual emptiness and urges listeners to be 'rich toward God' instead. He calls for self-examination regarding where one's true treasure lies and encourages a life of generosity and service to others.