C.H. Spurgeon emphasizes the importance of seeking God's guidance in all decisions, using David's example after his victory over the Philistines. Despite his previous success, David did not assume he could achieve victory again without consulting the Lord first. Spurgeon encourages Christians to rely on God's direction, warning against the folly of acting independently of divine guidance. He reminds believers to take their uncertainties to God and wait for His instruction before proceeding. The sermon calls for a deep reliance on God's providence in navigating life's challenges.