Mike Bickle emphasizes the significance of the apostolic prayer found in Ephesians 1:15-23, which seeks the spirit of wisdom and revelation for deeper intimacy with God. He highlights that this prayer addresses the greatest spiritual needs in our lives and the necessity of persistent prayer to receive God's glory. Bickle warns against complacency in faith, urging believers to actively seek God's presence and understanding through prayer. He explains that the spirit of revelation allows us to see and feel as God does, empowering us to fulfill our divine assignments. Ultimately, this prayer is a call to experience God's power and presence in our lives, transforming our hearts and minds.