Chuck Smith emphasizes the prophetic significance of Daniel 9:22, detailing the necessity of a Messiah for the Jewish people who were in captivity due to their sins and rebellion against God. He explains the promise of the Messiah, highlighting the timeline of 70 sevens leading to the coming of the 'Messiah the Prince' and the fulfillment of this prophecy with Jesus' entry into Jerusalem. Smith illustrates how the precise timing of these events, including the 173,880 days from the decree to rebuild Jerusalem to Jesus' triumphal entry, underscores God's divine plan and the importance of recognizing Jesus as the promised Savior.